HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86692579, compound → HCID 86692578, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86692579 | HCID 86692579 | — |
| Reactant | HCID 86692580 | HCID 86692580 | — |
| Product | HCID 86692578 | HCID 86692578 | 94.5% |
Reaction Steps
N-[6-(1,4-Dioxaspiro[4.5]dec-8-yl)-5-methylpyridin-3-yl]-1-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]-5-methyl-1H-pyrazole-4-carboxamide (274 mg) described in Example D196 was used in place of N-[6-(8-cyano-1,4-dioxaspiro[4.5]dec-8-yl)pyridin-3-yl]-5-methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazolecarboxamide in Example F2(1), and reacted and treated in a similar manner to give the titled compound (237 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150555B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-dbbf3cdd09b14425a58afa2e942105ae |
| Source note | uspto-grants-2015_10 |