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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1748640Generated: October 30, 2026

HCID 86692579, compound → HCID 86692578, compound

https://huagongshe.com/reaction/1748640

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86692579HCID 86692579—
ReactantHCID 86692580HCID 86692580—
ProductHCID 86692578HCID 8669257894.5%

Reaction Steps

N-[6-(1,4-Dioxaspiro[4.5]dec-8-yl)-5-methylpyridin-3-yl]-1-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]-5-methyl-1H-pyrazole-4-carboxamide (274 mg) described in Example D196 was used in place of N-[6-(8-cyano-1,4-dioxaspiro[4.5]dec-8-yl)pyridin-3-yl]-5-methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazolecarboxamide in Example F2(1), and reacted and treated in a similar manner to give the titled compound (237 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150555B2
Source datasetuspto-grants-2015_10
ORD IDord-dbbf3cdd09b14425a58afa2e942105ae
Source noteuspto-grants-2015_10