Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl Lactate | HCID 7344 | — |
| Reactant | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 346572 | HCID 346572 | — |
Reaction Steps
15 g of ethyl lactate and 10 g of 2-amino-2-methyl-1-propanol were mixed and subsequently heated to 110-115° C. for 3.5 hours. During the reaction, the ethanol formed was distilled off. After the reaction, the excess of ethyl lactate was removed by vacuum distillation (bottom temperature: 160° C., 7 mbar), using a vigreux column. 15.5 g of residual brown viscous liquid was collected, which was confirmed to be pure N-lactoyl 2-amino-2-methylpropanol by NMR analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09155329B2 |
|---|
| Source dataset | uspto-grants-2015_10 |
|---|
| ORD ID | ord-5ea3950e5bf94a078808b5427f690440 |
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| Source note | uspto-grants-2015_10 |
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