反应详情

温度

100 °C

In a N,N-dimethylformamide (DMF) solvent, a suspension of 3-bromo-4-hydroxybenzaldehyde (1.0 eq.) and 2-amino-4-(trifluoromethyl)benzenethiol (1.0 eq.) was heated at a temperature of 100° C. After cooling, DMF was removed therefrom under reduced pressure. Methylene chloride was added to the resultant solid, and the produced precipitate was filtered, and washed with methylene chloride to obtain a solid target product.

1. temperatureAfter cooling
2. customDMF was removed
3. additionMethylene chloride was added to the resultant solid
4. filtrationthe produced precipitate was filtered
5. washwashed with methylene chloride
6. customto obtain a solid target product