Hydrochloric Acid → HCID 70980463, compound

HRID 1749112Notes

Reaction equation

C(O[C:6](=O)[N:7](C)[C@H:8]([C:10](=[O:23])[NH:11][C:12]1[CH:13]=[CH:14][C:15]2[NH:16][C:17](=[O:22])[NH:18][CH2:19][C:20]=2[N:21]=1)[CH3:9])(C)(C)C.[ClH:26]>>[ClH:26].[CH3:6][NH:7][C@@H:8]([CH3:9])[C:10]([NH:11][C:12]1[CH:13]=[CH:14][C:15]2[NH:16][C:17](=[O:22])[NH:18][CH2:19][C:20]=2[N:21]=1)=[O:23]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 70980383HCID 70980383, compound

Product 1

HCID 70980463HCID 70980463, compound

Procedure

Methyl-[(S)-1-(2-oxo-1,2,3,4-tetrahydro-pyrido[3,2-d]pyrimidin-6-ylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester (67 mg, 0.19 mmol) was treated with HCl according to the General procedure 3 to afford the title compound (27 mg).

Sources & evidence

ORD record: ord-3932869452cd42e484aacb59c2a3dd17
Source dataset: uspto-grants-2015_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09155743B2

Reaction notes

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