N,N-Dimethylglycine → HCID 18723056, compound

Participants

Reaction Steps

N,N-dimethylglycine (0.8 g, 6.8 mmol) was dissolved in an aqueous solution of 70% ethylamine (5.7 g, 68 mmol), and the solution was placed in a closed vessel and stored at 5° C. for 3 days. The solution was concentrated under reduced pressure, and the resultant oily product was subjected to column chromatography, followed by extraction with a chloroform/methanol mixed solvent, to thereby obtain Exemplified Compound (6) (0.84 g, 94.4%) as a colorless oil.

Provenance & Evidence