Trifluoroacetic acid → HCID 118162172, compound

Participants

Reaction Steps

To a solution of tert-butyl 4-cyano-3-(trifluoromethoxy)phenethylcarbamate (150 mg, 0.45 mmol) in DCM (3 mL) was added TFA (1.5 mL). The resulting reaction mixture was stirred at room temperature for 1.5 h. The mixture was concentrated to afford the crude title product (120 mg, crude), which was used directly for next step without further purification. MS (ESI) m/z 231.1 [M+H]+.

Provenance & Evidence