Hydrochloric Acid → HCID 178446826, compound

Participants

Reaction Steps

200 mg of [(S)-3-Methyl-1-(4H-[1,2,4]triazole-3-sulfonylmethyl)-butyl]-carbamic acid tert-butyl ester were dissolved in 6 ml of dioxane and reacted with 2.2 ml of 4M hydrochloric acid in dioxane at rt for 16 h. The reaction was concentrated in vacuo and the resulting crude product was used without further purification. 120 mg (100%) of S)-3-Methyl-1-(4H-[1,2,4]triazole-3-sulfonylmethyl)-butylamine-hydrochloride were obtained.

Provenance & Evidence