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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1750367Generated: October 29, 2026

2-Morpholinoethylamine → 2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazole-4-carboxamide

https://huagongshe.com/reaction/1750367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MorpholinoethylamineHCID 408285—
Reactant2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazole-4-carboxylic acidHCID 86721202—
Product2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazole-4-carboxamideHCID 86721206—

Reaction Steps

Using 2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazole-4-carboxylic acid and 2-morpholinoethanamine and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09156837B2
Source datasetuspto-grants-2015_10
ORD IDord-a2fbec3857814bf48e8f9fe4d9ea8fce
Source noteuspto-grants-2015_10