4-Aminotetrahydropyran → HCID 71250806, compound

HRID 1750445Notes

Reaction equation

[C:1]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=2)=[C:8]([C:18]2[S:19][CH:20]=[C:21]([CH2:23][CH2:24][C:25]([OH:27])=O)[N:22]=2)[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].[NH2:28][CH:29]1[CH2:34][CH2:33][O:32][CH2:31][CH2:30]1>>[C:1]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=2)=[C:8]([C:18]2[S:19][CH:20]=[C:21]([CH2:23][CH2:24][C:25]([NH:28][CH:29]3[CH2:34][CH2:33][O:32][CH2:31][CH2:30]3)=[O:27])[N:22]=2)[CH:7]=[N:6]1)([CH3:2])([CH3:3])[CH3:4]

Participants

Reactant 2

HCID 4192234-Aminotetrahydropyran

HCID 86721286HCID 86721286, compound

Product 1

HCID 71250806HCID 71250806, compound

Procedure

Using the compound obtained in step 1 and 4-aminotetrahydropyran and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.

Workup

customby reaction and purification in the same manner as in the method

Sources & evidence

ORD record: ord-d45fd7e12940420aafae633e1e4b745e
Source dataset: uspto-grants-2015_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09156837B2

Reaction notes

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