HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 89655921, compound → Thieno[3,2-D]pyrimidine-7-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 89655921 | HCID 89655921 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Thieno[3,2-D]pyrimidine-7-carbaldehyde | HCID 55274736 | 31.2% |
Reaction Steps
7-hydroxymethyl-thieno[3,2-d]pyrimidine (250 mg, 1.56 mmol) was dissolved in dichloromethane (10 mL), added with MnO2 (1.36 g, 15.60 mmol), followed by stirring for 2 hours. The reaction mixture was filtered through a Celite pad under reduced pressure, and concentrated to obtain the title compound (80 mg, 30%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156852B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-efa5f07eb6cf48498bca6d465890d760 |
| Source note | uspto-grants-2015_10 |