反应详情

N-(1,3-diisopropyldibenzo[b,d]furan-4-yl)acetamide (15 g, 48 mmol) was suspended in the mixture of Concentrated HCl (125 mL) and MeOH (125 mL). The mixture was refluxed for 2 h and then cooled to room temperature. Saturated sodium carbonate was used to neutralize the solution. The residue was collected by filtration and redissolved in DCM. After dried over sodium sulfate, the solution was concentrated to give 1,3-diisopropyldibenzo[b,d]furan-4-amine (10.5 g, 81% yield) as brown solid.

1. temperatureThe mixture was refluxed for 2 h
2. filtrationThe residue was collected by filtration
3. dissolutionredissolved in DCM
4. dry with materialAfter dried over sodium sulfate
5. concentrationthe solution was concentrated