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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1750943Generated: November 3, 2026

Hydrochloric Acid → HCID 66652304, compound

https://huagongshe.com/reaction/1750943

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046786HCID 58046786—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652304HCID 66652304—

Reaction Steps

To tert-butyl 3-(2-(methoxycarbonyl)benzyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.12 g, 0.25 mmol) was added 4M solution of HCl in dioxane (2.5 mL). After stirring at room temperature for 90 minutes, the reaction mixture was concentrated in vacuo to obtain methyl 2-((4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09156840B2
Source datasetuspto-grants-2015_10
ORD IDord-c73f6d1680a5413496d9d17c09ad9934
Source noteuspto-grants-2015_10