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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1750956Generated: November 2, 2026

Hydrochloric Acid → HCID 66652293, compound

https://huagongshe.com/reaction/1750956

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046698HCID 58046698—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652293HCID 66652293—

Reaction Steps

To tert-butyl 3-(3-((2-(dimethylamino)-2-oxoethoxy)carbonyl)benzyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.26 g, 0.47 mmol) was added 4M solution of HCl in dioxane (5 mL). After stirring at room temperature for 2 hours, the reaction mixture was concentrated in vacuo to obtain 2-(dimethylamino)-2-oxoethyl 3-((4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09156840B2
Source datasetuspto-grants-2015_10
ORD IDord-80fb2e9676794c63afa54d4c00a89c3c
Source noteuspto-grants-2015_10