Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 2-(2,2,3,3,4,4,5,5,5-Nonafluoropentyl)oxirane | HCID 2775819 | — |
| Product | HCID 86612009 | HCID 86612009 | 93.2% |
Reaction Steps
To 8.7 g of morpholine, 27.6 g of 1,2-epoxy-4,4,5,5,6,6,7,7,7-nonafluoroheptane was added dropwise. The mixture was then stirred at 80° C. for 10 hours. The reaction mixture was directly purified by silica gel column chromatography, obtaining 33.8 g of 1-morpholino-4,4,5,5,6,6,7,7,7-nonafluoro-2-heptanol (yield 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09158191B2 |
|---|
| Source dataset | uspto-grants-2015_10 |
|---|
| ORD ID | ord-091d4c43dc574be09355a5fdfcb87eb9 |
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| Source note | uspto-grants-2015_10 |
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