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HRID1751543

反应详情

EQUATION

反应方程式

HRID 1751543 的结构方程式

REACTANTS

反应物

6
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：COC(=O)N[C@H](C(=O)O)C(C)C
HCID10942966

(S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid

C7H13NO4

结构：COC(=O)N[C@H](C(=O)O)[C@@H](C)OC
HCID59540170

未命名化合物

结构：COC(=O)N[C@H](C(=O)N1CC(=O)C[C@H]1C(=O)OCc1ccccc1)C(C)C
HCID59610664

未命名化合物

结构：Cl.O=C1CN[C@H](C(=O)OCc2ccccc2)C1
HCID86648889

未命名化合物

结构：COC(=O)N[C@H](C(=O)N1CC2(C[C@H]1c1ncc(-c3ccc(-c4ccc5c(ccc6nc([C@@H]7CCCN7)[nH]c65)c4)cc3)[nH]1)OCCO2)C(C)C
HCID178502290

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)N[C@H](C(=O)N1CC2(C[C@H]1c1ncc(-c3ccc(-c4ccc5c(ccc6nc([C@@H]7CCCN7C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC)[nH]c65)c4)cc3)[nH]1)OCCO2)C(C)C
HCID178502288

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the method employed to prepare (S)-benzyl 1-((S)-2-(methoxycarbonylamino)-3-methylbutanoyl)-4-oxopyrrolidine-2-carboxylate, except that methyl (S)-3-methyl-1-oxo-1-((S)-8-(5-(4-(2-((S)-pyrrolidin-2-yl)-1H-naphtho[1,2-d]imidazol-7-yl)phenyl)-1H-imidazol-2-yl)-1,4-dioxa-7-azaspiro[4.4]nonan-7-yl)butan-2-ylcarbamate 3× HCl salt and (2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid were used instead of (S)-benzyl 4-oxopyrrolidine-2-carboxylate hydrochloride and (S)-2-(methoxycarbonylamino)-3-methylbutanoic acid. MS (ESI) m/z 838.73 [M+H]+. (45 mg, 54%).