HRID1751547

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(O)[C@@H]1CC2(CN1C(=O)OCc1ccccc1)OCCO2

HCID12811387

未命名化合物

结构：Nc1cc(Br)ccc1NC(=O)C1CC2(CC2)CN1C(=O)OCc1ccccc1

HCID66620342

未命名化合物

结构：Nc1ccc(Br)cc1NC(=O)C1CC2(CC2)CN1C(=O)OCc1ccccc1

HCID66620480

未命名化合物

PRODUCTS

生成物

结构：Nc1cc(Br)ccc1NC(=O)[C@@H]1CC2(CN1C(=O)OCc1ccccc1)OCCO2

HCID67682377

未命名化合物

PROCEDURE

实验过程

Title compound was prepared in quantitative yield according to the method employed to make 6-(2-Amino-5-bromo-phenylcarbamoyl)-5-aza-spiro[2.4]heptane-5-carboxylic acid benzyl ester and 6-(2-Amino-4-bromo-phenylcarbamoyl)-5-aza-spiro[2.4]heptane-5-carboxylic acid benzyl ester, substituting (S)-5-(benzyloxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid with (S)-7-(benzyloxycarbonyl)-1,4-dioxa-7-azaspiro[4.4]nonane-8-carboxylic acid (357 mg, 99%).