Hydrochloric Acid → HCID 86708810, compound

Participants

Reaction Steps

A mixture of (2S,4S)-tert-butyl 2-(5-(7-(2-((2S,4S)-1-((R)-2-(methoxycarbonylamino)-2-phenylacetyl)-4-methylpyrrolidin-2-yl)-1H-imidazol-5-yl)-5,10-dihydrochromeno[5,4,3-cde]chromen-2-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidine-1-carboxylate (245 mg) and 5 mL 1.25N HCl in ethanol was stirred at room temperature overnight, then at 60° C. for 1 hour, then concentrated to an orange solid as an HCl salt (180 mg) that was used without further purification.

Provenance & Evidence