HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-5-dibenzylamino-1-methylpiperidin-2-one → HCID 28064098, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-5-dibenzylamino-1-methylpiperidin-2-one | HCID 59708472 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 28064098 | HCID 28064098 | 101.6% |
Reaction Steps
0.450 g (S)-5-dibenzylamino-1-methylpiperidin-2-one are suspended in 25 ml of methanol and hydrogenated with 0.150 g Pd/C 10% at a pressure of 3 bar and at a temperature of 60° C. After 16 hours the catalyst is removed by suction filtering and the filtrate is evaporated to dryness. 0.190 g of the product are obtained in the form of an oil. 1H NMR (400 MHz, DMSO): 2.76 (3H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09161927B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-5572e900498a42d38ec423e30f0d8dcb |
| Source note | uspto-grants-2015_10 |