HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrazole → 1-(4-Methoxyphenyl)-1H-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrazole | HCID 1048 | — |
| Reactant | 4-Bromoanisole | HCID 7730 | — |
| Product | 1-(4-Methoxyphenyl)-1H-pyrazole | HCID 12238131 | 80% |
Reaction Steps
Following General Procedure A (125° C., 24 hours), 1H-pyrazole (102 mg, 1.5 mmol) is coupled with 4-methoxybromobenzene (1.0 mmol). The crude product is purified by flash chromatography on silica gel to provide the desired product (80% GC yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162953B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-7f9fe7ef13804a338a1087a33d7872fb |
| Source note | uspto-grants-2015_10 |