HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → HCID 87391898, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Hydrogen phosphate | HCID 3681305 | — |
| Reactant | 794521-56-5 | HCID 11983903 | — |
| Reactant | HCID 67419345 | HCID 67419345 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 87391898 | HCID 87391898 | 92.5% |
Reaction Steps
Under reaction conditions analogous to the preparation of 5-methylsulfoxyoxindole, alkylation of 5-mercaptooxindole 1.99 g (12.05 mmol) with ethyl iodide 1.35 mL (16.7 mmol) in aqueous methanol at 50° C. in the presence of hydrogen phosphate provided 2.152 g of 5-ethylthiooxindole (92.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162981B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-63e128f906964c3eb3445ef94f3838ab |
| Source note | uspto-grants-2015_10 |