Hydrogen iodide → HCID 51355284, compound

HRID 1751986Notes

Reaction equation

HRID 1751986 reaction equation
[F:1][C:2]1[CH:3]=[C:4](B(O)O)[CH:5]=[CH:6][CH:7]=1.Cl[C:12]1[CH:17]=[C:16](Cl)[N:15]=[CH:14][N:13]=1.[IH:19]>>[I:19][C:12]1[CH:17]=[C:16]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([F:1])[CH:3]=2)[N:15]=[CH:14][N:13]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 27339863-Fluorophenylboronic acid

Product 1

HCID 51355284HCID 51355284, compound

Procedure

The compound was prepared according to Example 1 using 3-fluorophenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-f457eb542482410a95a010479046943f
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

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