Hydrogen iodide → HCID 51355286, compound

HRID 1751988Notes

Reaction equation

HRID 1751988 reaction equation
[F:1][C:2]1[C:7](B(O)O)=[CH:6][CH:5]=[CH:4][N:3]=1.Cl[C:12]1[CH:17]=[C:16](Cl)[N:15]=[CH:14][N:13]=1.[IH:19]>>[I:19][C:12]1[CH:17]=[C:16]([C:7]2[C:2]([F:1])=[N:3][CH:4]=[CH:5][CH:6]=2)[N:15]=[CH:14][N:13]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 27832702-Fluoropyridine-3-boronic acid

Product 1

HCID 51355286HCID 51355286, compound

Procedure

The compound was prepared according to Example 1 using 2-fluoropyridine-3-boronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-df75a8b86b194eda83a15bc0bec0940c
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

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