Hydrogen iodide → HCID 51355289, compound

HRID 1751990Notes

Reaction equation

HRID 1751990 reaction equation
[F:1][C:2]1[CH:3]=[C:4](B(O)O)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].Cl[C:14]1[CH:19]=[C:18](Cl)[N:17]=[CH:16][N:15]=1.[IH:21]>>[I:21][C:14]1[CH:19]=[C:18]([C:4]2[CH:5]=[CH:6][C:7]([O:8][CH3:9])=[C:2]([F:1])[CH:3]=2)[N:17]=[CH:16][N:15]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 27821943-Fluoro-4-methoxyphenylboronic acid

Product 1

HCID 51355289HCID 51355289, compound

Procedure

The compound was prepared according to Example 1 using 3-fluoro-4-methoxyphenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-02391e1f25124d8c8db0dea2e3d73aeb
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

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