Hydrogen iodide → HCID 136030444, compound

HRID 1751992Notes

Reaction equation

HRID 1751992 reaction equation
FC(F)(F)[O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1B(O)O.Cl[C:16]1[CH:21]=[C:20](Cl)[N:19]=[CH:18][N:17]=1.[IH:23]>>[I:23][C:16]1[CH:21]=[C:20]([C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[OH:3])[N:19]=[CH:18][N:17]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 27772042-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)

Product 1

HCID 136030444HCID 136030444, compound

Procedure

The compound was prepared according to Example 1 using 2-trifluoromethoxyphenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-2b94e0b3e2dc4942a3835a98714972d3
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

Loading…