Hydrogen iodide → HCID 51355293, compound

HRID 1751993Notes

Reaction equation

HRID 1751993 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1B(O)O.Cl[C:13]1[CH:18]=[C:17](Cl)[N:16]=[CH:15][N:14]=1.[IH:20]>>[I:20][C:13]1[CH:18]=[C:17]([C:3]2[CH:4]=[CH:5][C:6]([F:8])=[CH:7][C:2]=2[F:1])[N:16]=[CH:15][N:14]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 27343342,4-Difluorophenylboronic acid

Product 1

HCID 51355293HCID 51355293, compound

Procedure

The compound was prepared according to Example 1 using 2,4-difluorophenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-31c0d19651fe40b390c8cd209b5ea5ba
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

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