Hydrogen iodide → HCID 51355567, compound

HRID 1751994Notes

Reaction equation

HRID 1751994 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH3:9])[C:3]=1B(O)O.Cl[C:14]1[CH:19]=[C:18](Cl)[N:17]=[CH:16][N:15]=1.[IH:21]>>[I:21][C:14]1[CH:19]=[C:18]([C:3]2[C:4]([O:8][CH3:9])=[CH:5][CH:6]=[CH:7][C:2]=2[F:1])[N:17]=[CH:16][N:15]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 3294524(2-Fluoro-6-methoxyphenyl)boronic acid

Product 1

HCID 51355567HCID 51355567, compound

Procedure

The compound was prepared according to Example 1 using 2-fluoro-6-methoxyphenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-c5c742b12b5a4db88a1f443a8d8f15ab
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

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