Hydrogen iodide → HCID 51355574, compound

HRID 1751998Notes

Reaction equation

C([O:5][CH2:6][C:7]1[CH:8]=[C:9](B(O)O)[CH:10]=[CH:11][CH:12]=1)(C)(C)C.Cl[C:17]1[CH:22]=[C:21](Cl)[N:20]=[CH:19][N:18]=1.[IH:24]>>[I:24][C:17]1[CH:22]=[C:21]([C:9]2[CH:10]=[CH:11][CH:12]=[C:7]([CH2:6][OH:5])[CH:8]=2)[N:20]=[CH:19][N:18]=1

Participants

Reactant 3

HCID 24841Hydrogen iodide

HCID 709434,6-Dichloropyrimidine

HCID 37738083-tert-Butoxymethylphenylboronic acid

Product 1

HCID 51355574HCID 51355574, compound

Procedure

The compound was prepared according to Example 1 using 3-tert-butyloxymethylphenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

customThe compound was prepared

Sources & evidence

ORD record: ord-1660ec515acc4166b4dffcebd8650317
Source dataset: uspto-grants-2015_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09162987B2

Reaction notes

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