Hydrogen iodide → HCID 51355572, compound

HRID 1752003Notes

Reaction equation

HRID 1752003 reaction equation
[F:1][C:2]1[CH:3]=[C:4](B(O)O)[CH:5]=[CH:6][C:7]=1[F:8].Cl[C:13]1[CH:18]=[C:17](Cl)[N:16]=[CH:15][N:14]=1.[IH:20]>>[I:20][C:13]1[CH:18]=[C:17]([C:4]2[CH:5]=[CH:6][C:7]([F:8])=[C:2]([F:1])[CH:3]=2)[N:16]=[CH:15][N:14]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 27343373,4-Difluorobenzeneboronic acid

Product 1

HCID 51355572HCID 51355572, compound

Procedure

The compound was prepared according to Example 1 using 3,4-difluorophenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-70be0a28403244e69714e94b6504ca0e
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

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