Hydrogen iodide → HCID 51355843, compound

HRID 1752008Notes

Reaction equation

HRID 1752008 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2B(O)O)[CH:4]=[CH:3][CH:2]=1.Cl[C:15]1[CH:20]=[C:19](Cl)[N:18]=[CH:17][N:16]=1.[IH:22]>>[I:22][C:15]1[CH:20]=[C:19]([C:9]2[CH:8]=[CH:7][CH:6]=[C:5]3[C:10]=2[N:1]=[CH:2][CH:3]=[CH:4]3)[N:18]=[CH:17][N:16]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 27343808-Quinolineboronic acid

Product 1

HCID 51355843HCID 51355843, compound

Procedure

The compound was prepared according to Example 1 using quinolin-8-boronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-886277f08e3d47f39903d538e6256b3e
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

Loading…