Hydrogen iodide → HCID 51355846, compound

HRID 1752009Notes

Reaction equation

HRID 1752009 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3](B(O)O)[CH:2]=1.Cl[C:15]1[CH:20]=[C:19](Cl)[N:18]=[CH:17][N:16]=1.[IH:22]>>[I:22][C:15]1[CH:20]=[C:19]([C:3]2[CH:2]=[N:1][C:10]3[C:5]([CH:4]=2)=[CH:6][CH:7]=[CH:8][CH:9]=3)[N:18]=[CH:17][N:16]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 2734663Quinoline-3-boronic acid

Product 1

HCID 51355846HCID 51355846, compound

Procedure

The compound was prepared according to Example 1 using quinolin-3-boronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-b86bf930f9aa4a329cf4ae70b1a8f217
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

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