Hydrogen iodide → HCID 51356107, compound

HRID 1752010Notes

Reaction equation

HRID 1752010 reaction equation
[CH:1]1[C:10]2[CH:9]=[CH:8][CH:7]=[C:6](B(O)O)[C:5]=2[CH:4]=[CH:3][N:2]=1.Cl[C:15]1[CH:20]=[C:19](Cl)[N:18]=[CH:17][N:16]=1.[IH:22]>>[I:22][C:15]1[CH:20]=[C:19]([C:6]2[CH:7]=[CH:8][CH:9]=[C:10]3[C:5]=2[CH:4]=[CH:3][N:2]=[CH:1]3)[N:18]=[CH:17][N:16]=1

Participants

4

Reactant 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 599474Isoquinoline-5-boronic acid

Product 1

HCID 51356107HCID 51356107, compound

Procedure

The compound was prepared according to Example 1 using isoquinolin-5-boronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-90202efdf0f6411485116e03ad945013
Source dataset
uspto-grants-2015_10
Patent number
US09162987B2

Reaction notes

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