Hydrochloric Acid → Hydrochloric Acid

Participants

Reaction Steps

A stirred solution of tert-butyl 3-(1-methyl-2-oxo-1,2-dihydroquinolin-6-yl)pyrrolidine-1-carboxylate (1 mg) in CH2Cl2 (2 mL) was treated with 4 M HCl in dioxane (1 mL, 4 mmol). The mixture was stirred at rt for 3 h and concentrated to leave 1-methyl-6-(pyrrolidin-3-yl)quinolin-2(1H)-one as its HCl salt (1 mg). LC-MS Method 1 tR=1.48 min, m/z=229.

Provenance & Evidence