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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1752307Generated: October 29, 2026

Trifluoroacetic acid → HCID 58171552, compound

https://huagongshe.com/reaction/1752307

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 58171610HCID 58171610—
SolventDichloromethaneHCID 6344—
ProductHCID 58171552HCID 5817155295%

Reaction Steps

To a solution of tert-butyl 3-(5-methoxypyrimidin-2-yl)pyrrolidine-1-carboxylate (13 mg, 0.047 mmol) in dry CH2Cl2 (0.5 mL) was added TFA (20% in CH2Cl2, 2 mL) at 0° C. The formed solution was stirred at rt for 2 h. The reaction mixture was concentrated in vacuo to give the crude product (8 mg), which was used for next step without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09163012B2
Source datasetuspto-grants-2015_10
ORD IDord-3f99222d30da414fb2480ca7f83db2c7
Source noteuspto-grants-2015_10