HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 58171552, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 58171610 | HCID 58171610 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 58171552 | HCID 58171552 | 95% |
Reaction Steps
To a solution of tert-butyl 3-(5-methoxypyrimidin-2-yl)pyrrolidine-1-carboxylate (13 mg, 0.047 mmol) in dry CH2Cl2 (0.5 mL) was added TFA (20% in CH2Cl2, 2 mL) at 0° C. The formed solution was stirred at rt for 2 h. The reaction mixture was concentrated in vacuo to give the crude product (8 mg), which was used for next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163012B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-3f99222d30da414fb2480ca7f83db2c7 |
| Source note | uspto-grants-2015_10 |