HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 68109996, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | HCID 68110177 | HCID 68110177 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 68109996 | HCID 68109996 | — |
Reaction Steps
In a mixture of 5 ml DCM and 2.5 ml TFA was dissolved 345 mg (1.26 mmol) 5-difluoromethyl-3-nitro-pyridine-2-carboxylic acid tert-butyl ester and the reaction mixture was stirred for 4 h. Toluene was added and the solvents were evaporated to provide the title compound as colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163011B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-ad09ccdb4d5a4661b37e1ab9c2e6c5b3 |
| Source note | uspto-grants-2015_10 |