反应详情

2 M HCl in Et2O (1.8 L) was added to a solution of compound 7a (92.8 g, 0.24 moles) in MeOH (500 mL). The mixture was stirred for 3 hours at room temperature then the resulting solid was filtered and dried to give 5-methoxy-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamide hydrochloride 7b (61.1 g, 89% yield).

1. filtrationthe resulting solid was filtered
2. customdried