HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-4-(aminomethyl)piperidine → Tert-butyl 4-({[(5-bromo-1H-indazol-3-yl)carbonyl]amino}methyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-4-(aminomethyl)piperidine | HCID 736817 | — |
| Reactant | 5-bromo-1H-indazole-3-carboxylic Acid | HCID 7157358 | — |
| Reactant | HCID 89767420 | HCID 89767420 | — |
| Product | Tert-butyl 4-({[(5-bromo-1H-indazol-3-yl)carbonyl]amino}methyl)piperidine-1-carboxylate | HCID 89767452 | — |
Reaction Steps
Tert-butyl 4-({[(5-bromo-1H-indazol-3-yl)carbonyl]amino}methyl)piperidine-1-carboxylate 11a was prepared, according to the procedure described for compound 7, from 5-bromo-1H-indazole-3-carboxylic acid and tert-butyl 4-(aminomethyl)piperidine-1-carboxylate. Yield: 40.6 g, 87%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163013B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-960c9831dbd24826ba6a92c0b1d4dcd7 |
| Source note | uspto-grants-2015_10 |