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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1752605Generated: November 3, 2026

Morpholine → HCID 78210284, compound

https://huagongshe.com/reaction/1752605

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantHCID 90421601HCID 90421601—
SolventEthanolHCID 702—
ProductHCID 78210284HCID 78210284123%

Reaction Conditions

Temperature90 °C

Reaction Steps

Morpholine (0.355 ml, 4.08 mmol) was added to a solution of 7-chloro-5-methyl-2-(2-quinolin-2-yl-ethyl)-5H-pyrrolo[3,4-c]pyridine-1,3,6-trione (0.5 g, 1.36 mmol, see Example c1)) in EtOH (30 ml) and the reaction was stirred at 90° C. for 16 h. The solvent was removed to give the title compound (0.7 g, 123% yield), which was used in the next steps without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09163019B2
Source datasetuspto-grants-2015_10
ORD IDord-65e14bbc0d944e79ae0a9ea66efdeaac
Source noteuspto-grants-2015_10