1-Methylpiperazine → HCID 86295427, compound

HRID 1752606Notes

Reaction equation

Cl[C:2]1[C:7](=[O:8])[N:6]([CH3:9])[CH:5]=[C:4]2[C:10](=[O:26])[N:11]([CH2:14][CH2:15][C:16]3[CH:25]=[CH:24][C:23]4[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=4)[N:17]=3)[C:12](=[O:13])[C:3]=12.[CH3:27][N:28]1[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1>>[CH3:9][N:6]1[C:7](=[O:8])[C:2]([N:31]2[CH2:32][CH2:33][N:28]([CH3:27])[CH2:29][CH2:30]2)=[C:3]2[C:12](=[O:13])[N:11]([CH2:14][CH2:15][C:16]3[CH:25]=[CH:24][C:23]4[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=4)[N:17]=3)[C:10](=[O:26])[C:4]2=[CH:5]1

Participants

Reactant 2

HCID 531671-Methylpiperazine

HCID 90421601HCID 90421601, compound

Product 1

HCID 86295427HCID 86295427, compound

Procedure

The title compound was prepared in analogy to the process described in Example 1 starting from 7-chloro-5-methyl-2-(2-quinolin-2-yl-ethyl)-5H-pyrrolo[3,4-c]pyridine-1,3,6-trione (see Example c1)) and 1-methyl-piperazine.

Sources & evidence

ORD record: ord-1fc60bb4db5341f39f502a673e625601
Source dataset: uspto-grants-2015_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09163019B2

Reaction notes

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