反应详情

Prepared according to Method M (Example 206) using [4-(trifluoromethyl)-1H-pyrazol-1-yl]acetic acid (Preparation 74) and (5-aminopyridin-3-yl)[7-fluoro-1-(2-hydroxy-1-methylethyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]methanone (Enantiomer 2, Preparation 26). The residue was purified using preparative TLC eluting with 5% MeOH in EtOAc. LCMS (5 minute run) Rt=2.85 minutes MS m/z 491 [M+H]+

1. customPrepared
2. customThe residue was purified
3. washeluting with 5% MeOH in EtOAc
4. customLCMS (5 minute run) Rt=2.85 minutes MS m/z 491