HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[4-(trifluoromethyl)-1H-pyrazol-1-yl]acetic acid → HCID 118341208, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[4-(trifluoromethyl)-1H-pyrazol-1-yl]acetic acid | HCID 64176482 | — |
| Reactant | HCID 90093760 | HCID 90093760 | — |
| Product | HCID 118341208 | HCID 118341208 | — |
Reaction Steps
Prepared according to Method M (Example 206) using [4-(trifluoromethyl)-1H-pyrazol-1-yl]acetic acid (Preparation 74) and (5-aminopyridin-3-yl)[7-fluoro-1-(2-hydroxy-1-methylethyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]methanone (Enantiomer 2, Preparation 26). The residue was purified using preparative TLC eluting with 5% MeOH in EtOAc. LCMS (5 minute run) Rt=2.85 minutes MS m/z 491 [M+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163021B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-5749e936a62a46e0b80de30a2c772007 |
| Source note | uspto-grants-2015_10 |