反应详情

Prepared according to Method M (Example 206) at 60° C. for 16 hours followed by 70° C. for a further 16 hours using (2-aminopyridin-4-yl)-(1-isopropyl-1H-pyrrolo[3,2-c]pyridin-3-yl)methanone (Preparation 20) and [4-cyano-3-(trifluoromethyl)phenyl]acetic acid (Preparation 95). Purified using silica gel column chromatography eluting with 5-7% MeOH in DCM.

1. customPrepared
2. waitfollowed by 70° C. for a further 16 hours
3. customPurified
4. washeluting with 5-7% MeOH in DCM