HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Cyano-3-(trifluoromethyl)phenyl)acetic acid → HCID 118341215, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Cyano-3-(trifluoromethyl)phenyl)acetic acid | HCID 70817381 | — |
| Reactant | HCID 90093478 | HCID 90093478 | — |
| Product | HCID 118341215 | HCID 118341215 | — |
Reaction Steps
Prepared according to Method M (Example 206) at 60° C. for 16 hours followed by 70° C. for a further 16 hours using (2-aminopyridin-4-yl)-(1-isopropyl-1H-pyrrolo[3,2-c]pyridin-3-yl)methanone (Preparation 20) and [4-cyano-3-(trifluoromethyl)phenyl]acetic acid (Preparation 95). Purified using silica gel column chromatography eluting with 5-7% MeOH in DCM.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163021B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-c95aad1dd9894bd2974ce1ae6eb1d079 |
| Source note | uspto-grants-2015_10 |