HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropyl iodide → HCID 90093605, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropyl iodide | HCID 6362 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-bromo-7-fluoro-1H-pyrrolo[3,2-c]pyridine | HCID 53412607 | — |
| Product | HCID 90093605 | HCID 90093605 | 56% |
Reaction Steps
Prepared according to the method described for Preparation 45 using 3-bromo-7-fluoro-1H-pyrrolo[3,2-c]pyridine (Preparation 48), 2-iodopropane and potassium carbonate as base. Purified using silica gel column chromatography eluting with 100% heptanes to 50:50 Heptane:EtOAc to afford the title compound (845 mg, 56%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163021B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-651c583086984c52905f0f248aae33ea |
| Source note | uspto-grants-2015_10 |