Acetic Acid → 1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-hydroxyphenyl)-4,5,6,7-tetrahydro-

HRID 175334Notes

Reaction equation

HRID 175334 reaction equation
[C:11]1(=[O:21])[C:12]2=[C:13]([C:14](=[O:15])[O:16]1)[CH2:17][CH2:18][CH2:19][CH2:20]2.[CH3:22][C:23](=[O:24])[OH:25].[Cl:1][c:2]1[c:3]([OH:10])[cH:4][c:5]([NH2:9])[c:6]([F:8])[cH:7]1>>[Cl:1][c:2]1[c:3]([OH:10])[cH:4][c:5]([N:9]2[C:11](=[O:16])[C:12]3=[C:13]([C:14]2=[O:15])[CH2:17][CH2:18][CH2:19][CH2:20]3)[c:6]([F:8])[cH:7]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 124753,4,5,6-Tetrahydrophthalic anhydrideHCID 1586545-Amino-2-chloro-4-fluorophenol

Product 1

HCID 1586511H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-hydroxyphenyl)-4,5,6,7-tetrahydro-

Sources & evidence

ORD record
ord-91551e6dd7af475ab3f4b9975cb351b6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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