反应详情

In 200 g of acetic acid was dissolved 26.6 g of bis[4-[2-(2-methoxyethoxy)ethoxy]phenyl]sulfide obtained in Synthesis Example 1-42. While the solution was maintained at an internal temperature of 30° C., 6.4 g of 35 wt % aqueous hydrogen peroxide was added dropwise. The reaction solution was aged at room temperature for 12 hours, after which under ice cooling, a mixture of 0.5 g sodium thiosulfate pentahydrate and 20 g water was added dropwise to quench the reaction. The solution was combined with 200 g of toluene and 100 g of water. The organic layer was separated, washed with water, and concentrated in vacuum, obtaining 26.1 g of the target compound, bis[4-[2-(2-methoxyethoxy)ethoxy]phenyl]sulfoxide as oily matter. Yield 95%.

1. customobtained in Synthesis Example 1-42
2. additionwas added dropwise
3. additionwas added dropwise
4. customto quench
5. customthe reaction
6. customThe organic layer was separated
7. washwashed with water
8. concentrationconcentrated in vacuum