Benzyl Bromide → HCID 9864573, compound

HRID 1753751Notes

Reaction equation

HRID 1753751 reaction equation
[CH3:1][C:2]1[C:14]2[NH:13][C:12]3[C:7](=[CH:8][CH:9]=[C:10]([OH:15])[CH:11]=3)[C:6]=2[CH:5]=[CH:4][N:3]=1.Br[CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH3:1][C:2]1[C:14]2[N:13]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[C:12]3[C:7](=[CH:8][CH:9]=[C:10]([O:15][CH2:6][C:7]4[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=4)[CH:11]=3)[C:6]=2[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 178432657HCID 178432657, compound

Product 1

HCID 9864573HCID 9864573, compoundYield 66%

Procedure

The title compound was synthesized from 1-methyl-7-hydroxy-β-carboline (1 g, 3.173 mmol) in presence of 1-bromomethylbenzene (1.085 g, 6.346 mmol) as described here above.

Sources & evidence

ORD record
ord-b065e69a99894100ac9478ec40acd2a0
Source dataset
uspto-grants-2015_10
Patent number
US09168247B2

Reaction notes

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