HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzaldehyde → 1-(Bromomethyl)-4-(propane-2-sulfonyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | Sodium propane-2-sulfinate | HCID 23685748 | — |
| Reactant | 3-Fluoro-4-(methylsulphonyl)benzyl bromide | HCID 67219065 | — |
| Product | 1-(Bromomethyl)-4-(propane-2-sulfonyl)benzene | HCID 67219758 | — |
Reaction Steps
The titled compound is prepared analogously to 4-bromomethyl-2-fluoro-1-methanesulfonyl-benzene by replacing 3,4-difluorobenzaldehyde with 4-fluorobenzaldehyde and by replacing methane sulfinic acid sodium salt with 2-propanesulfinic acid sodium salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09169251B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-f1ed964fb9f14c61ad22a936fdc66571 |
| Source note | uspto-grants-2015_10 |