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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1754521Generated: October 29, 2026

4-Fluoro-3-methoxybenzenesulfonyl chloride → 6-Cyanopyridine-3-sulfonyl chloride

https://huagongshe.com/reaction/1754521

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-3-methoxybenzenesulfonyl chlorideHCID 2783408—
Reactant5-Aminopyridine-2-carbonitrileHCID 3871395—
Product6-Cyanopyridine-3-sulfonyl chlorideHCID 47003190—

Reaction Steps

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 5-amino-pyridine-2-carbonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09169251B2
Source datasetuspto-grants-2015_10
ORD IDord-68eaa0d3232e433498dcecae94ad0f03
Source noteuspto-grants-2015_10