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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1754530Generated: October 28, 2026

4-Chloro-3-fluoroaniline → 4-Chloro-3-fluorobenzene-1-sulfonyl chloride

https://huagongshe.com/reaction/1754530

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-3-fluoroanilineHCID 2736511—
Reactant4-Fluoro-3-methoxybenzenesulfonyl chlorideHCID 2783408—
Product4-Chloro-3-fluorobenzene-1-sulfonyl chlorideHCID 43566192—

Reaction Steps

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 4-chloro-3-fluoro-phenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09169251B2
Source datasetuspto-grants-2015_10
ORD IDord-e50275ece1fa427f84480e2c76ed939c
Source noteuspto-grants-2015_10