Hydrochloric Acid → HCID 86679813, compound

Participants

Reaction Steps

To a solution of 8-chloro-7-(pyrid-2-yl)-5-(2,2,2-trifluoroethyl)-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one (532 mg, 1.40 mmol) in a DCM/MeOH mixture (50/50) is added a 4M solution of hydrogen chloride in dioxane (3.5 mL, 14.1 mmol). The suspension is stirred at room temperature and then filtered and dried under vacuum to give 420 mg of a white powder (hydrochloride, 0.06 H2O; yield: 72%)

Provenance & Evidence